AQUAFRESH ENAMELOCK FORMULA
Clinical trials are considered to be the gold standard test for any healthcare product. However, in the field of caries research use of placebo-controlled studies is limited due to ethical considerations associated with the risk of permanent damage to the natural dentition, and the risk from use of x-rays to monitor caries development. [Zero, 1995] Aquafresh scientists at GlaxoSmithKline therefore use in situ* clinical studies and in vitro remin-/demineralization models† to evaluate the efficacy of oral healthcare products in the field of caries research.
By following the links below short summaries of the studies used to evaluate the efficacy of Enamelock formula can be found. As dentifrice formulations across the globe have different standard fluoride concentrations, the study outcomes for both the 1450ppm fluoride and 1150ppm fluoride formulations are available.
Aquafresh Fresh and Minty Enamelock Formula (1450ppm fluoride)
Aquafresh Advanced Enamelock Formula
(1150ppm fluoride)
* Dental appliance with enamel specimens is placed in the subject's mouth.
† Enamel specimens are subjected to cyclical periods of simulated plaque acid challenge, a slurry of the test dentifrice and human saliva.