AQUAFRESH ENAMELOCK FORMULA
Aquafresh Advanced Enamelock Formula (1150ppm formulation)
- The enamel fluoride uptake and remineralization efficacy (as measured by changes in surface microhardness) of Aquafresh Advanced Enamelock Formula was compared with other commercially available dentifrice formulations and the previous Aquafresh Advanced formulation in an in vitro demin-/remineralization cycling study. [Lippert et al, 2009]
- The results of this study showed that Aquafresh Advanced Enamelock Formula, compared with other dentifrices tested, promotes: [Lippert et al, 2009]
- – significantly greater fluoride uptake
- – superior enamel strengthening.
Aquafresh Advanced Enamelock Formula promotes greater fluoride uptake and superior enamel strengthening compared with other dentifrices tested
[Lippert et al, 2009]
Aim
- To evaluate the efficacy of Aquafresh Advanced Enamelock Formula versus other commercially available dentifrice formulations at promoting enamel fluoride uptake and superior enamel strength, pre- and post-simulated plaque acid challenge.
Method
- This study used a well-established model of remineralization and demineralization.
- n=27 human enamel specimens with artificial lesions were treated for 20 days according to a
24-hour cycling regimen comprising one 4-hour acid challenge and four 1-minute treatments with slurries of the test dentifrice and human saliva. - Remineralization and resistance to demineralization (following simulated plaque acid challenge) were assessed as change in surface microhardness from baseline.
- Enamel fluoride uptake was evaluated using the microdrill technique.
Results
Enamel remineralization
- Aquafresh Advanced Enamelock Formula delivered significantly greater fluoride uptake (p<0.05; Figure 1), and a superior change in enamel surface microhardness (p<0.05; Figure 2) compared with another commercially available dentifrice and two previous Aquafresh formulations.
Figure 1: Aquafresh Advanced Enamelock Formula promotes significantly greater enamel
fluoride uptake compared with other dentifrices tested (p<0.05)
Figure 2: Aquafresh Enamelock Formula provides significantly superior enamel strength
compared with other dentifrices tested (p<0.05)
Enamel demineralization
- Following 16 hours of simulated plaque acid challenge enamel samples treated with Aquafresh Advanced Enamelock Formula maintained a greater increase in surface microhardness from baseline (28.2±2.2, p<0.05) compared with other dentifrices tested.
Conclusion
- 20-days treatment with Aquafresh Advanced Enamelock Formula provides superior enamel strength and greater fluoride uptake compared with two previous Aquafresh formulations and another commercially available dentifrice. [Lippert et al, 2009]